The Komedia is a Brighton Institution and celebrates its birthday tonight in a suitably raucous fashion. The Komedia began in 1994, founded by the directors of the Umbrella Theatre Company, and styled on the cabaret spaces they’d experienced touring Europe. It moved to its current premises in 1999, turning a ramshackle labyrinthine building that housed a hippy-style market (before that a Tesco) into a labyrinthine building housing a bar-venue-cinema complex, with the central hub in the large basement.

Tommy Tiernan is something of an institution in his native Ireland, as a stand-up comic, newspaper columnist, sometime chat show host and full-time controversialist. Now his appearance as Da Gerry in Channel 4's Derry Girls has brought him to a wider audience – both geographically and generationally – and deservedly so.

Angela Barnes is one of life’s pessimists, she tells us at the top of the hour, but she’s trying not to be so world-weary, and to turn negatives into positives. And, while there’s so much awfulness going on around us, why not try to lighten the mood a little?

Ed Gamble starts the hour by telling us why his latest show is called Blizzard; he and a bunch of comic friends we stranded in New York by bad weather and it made the news - yet, strangely, the headline wasn’t a play on his name - a gift for hacks - but on the monicker of one of his mates. Cue faux outrage.

Have you ever felt the hot shame of saying or doing the wrong thing? Not just embarrassment – that's for amateurs, says Lou Sanders in her wonderfully honest and revealing show Shame Pig, in which she essays some of her life's red-faced moments. Embarrassment is fleeting and lends itself to a good anecdote (or a fine joke in a stand-up set), she says, while shame is a much more corrosive emotion, and one that young women in particular burden themselves with unnecessarily.

Lost Voice Guy – aka Lee Ridley – won Britain’s Got Talent last year. He's a unique talent in that his cerebral palsy means he is unable to speak, and so he delivers his comedy through a synthesizer controlled via his iPad.

Daniel Sloss's latest show is called X, to denote his 10th show. The Scottish comic started in comedy as a teenager in 2009 when a lot of his material was knob and wank gags, but in recent years his work has had a progressively edgier feel, including shows that delved into his sister's death from cerebral palsy and the childhood grooming from which he had a lucky escape.

There's a story in James Acaster's superb new show at the Phoenix Theatre which hangs on him being the first UK comic to shoot several Netflix specials. He doesn't tells us this to boast; far from it. It's to set up another long-form gag, one of several lengthy and interconnected stories he tells in Cold Lasagne Hate Myself 1999, the two-part tale of the best and worst years of his life.

Suited and booted, Tom Allen and Suzi Ruffell presented this gala preview to the Leicester Comedy Festival, which is now in its 26^th year and starts next month. The comics, who do an occasional podcast together called Like Minded, make an engaging double act – although their solo shows couldn't be more different.

As openings go, the first night of Hari Kondabolu's standup residency at Soho Theatre was pretty memorable, so get to American Hour in good time as he is trying to pull off the same trick when he can (no spoilers, but it involves quite a bit of planning for each performance, so he may not). It's a clever spoof on the “all Asians look the same to me” trope so beloved of white racists.